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It is a coordination complex: a tripeptide ligand, glycyl-histidyl-lysine, bound to copper in the divalent state through the N-terminal amine, a deprotonated backbone amide nitrogen and the imidazole nitrogen of the histidine side chain

If you take them with ginkgo biloba or garlic supplements, they can affect blood clotting and increase the risk of bleeding

The committees recommendations overruled the recommendations of the agencys own scientists who said there was too little evidence of their safety and efficacy in humans