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NICE guidance (NG238) does not currently recommend GLP-1 receptor agonists specifically for dyslipidaemia treatment, though their cardiovascular benefits are recognised in appropriate patient populations
To note, Wegovy (semaglutide) is a higher dose semaglutide formulation which has been approved by the TGA for chronic weight management at a maximum dose of 2.4 mg weekly
Something that isn't bitter
Efficient GST activity and adequate glutathione are thus important for neutralizing patulin.[ref] Overall, combinations of slower CYP1A2/CYP3A4 alleles with reduced-function GST or UGT variants can leave someone more vulnerable at normal dietary exposure levels, because reactive mycotoxin intermediates may not be cleared efficiently
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