In supplements, glutathione is generally in its "reduced" (GSH) form, the active antioxidant
J Biol Chem 269(10):73427348 Pushpa-Rekha TR, Burdsall AL, Oleksa LM, Chisolm GM, Driscoll DM (1995) Rat phospholipid-hydroperoxide glutathione peroxidase: cDNA cloning and identification of multiple transcription and translation start sites
Tuna et al., 2008
Damaged AECs release pro-inflammatory and pro-fibrotic mediators, including interleukin (IL) -1 and tumor necrosis factor (TNF) -, which promote fibroblast recruitment, inflammatory cell activation (e.g., neutrophils, Th17, gdT cells), and myofibroblast differentiation, ultimately leading to ECM accumulation and fibrotic tissue remodeling [20, 29, 33, 34]