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Li stated that while these questions are certainly interesting, he is not yet able to provide an answer based solely on the data collected from TriNetX

Interestingly, GLP-1/exendin-4 administration in obese Zucker rats, which also develop insulin resistance, hyperinsulinemia and hyperlipidemia, reduces food intake and induced weight loss, which applies to lean rats, too

Activation of spinal cord GLP-1Rs was shown to suppress pain hypersensitivity 24 , suggesting that GLP-1R signaling in laminae IIIII may be important in the regulation of the processing of sensory information