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In diabetics and patients with renal insufficiency, the excretion of carnitine is increased
This distinction alone fundamentally changes the treatment calculus, because chronic conditions typically require chronic treatment, and obesity is a chronic condition
Several are now underway including the REMODEL T1D trial (semaglutide and kidney disease in T1D) and the SURPASS-T1D phase 3 trials (tirzepatide in T1D) with results expected in the coming years
Min SY, Kim HS, Jung EJ, Jung EJ, Jee CD, Kim WH
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