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The connection between IBS and weight changes isnt simple, and its different for everyone

The inflammatory phase is directed by cytokines, matrix proteins, and enzymes

Conversely, another possibility is that a lower C4B copy number might protect the stability of the host microbiome to some extent by reducing the excessive clearance of beneficial microbes mediated by C4B

However, more human studies are needed to understand how it translates into real-life outcomes, Venner says and warns against focusing too heavily on a single prebiotic or bacterial strain