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Not because it is a magic pill
The FLOW trial notably demonstrated a reduction in the risk of major adverse cardiovascular events, death from cardiovascular causes and all-cause mortality with semaglutide in adults with CKD and T2D, with prespecified analyses suggesting that these outcomes were consistent in patients across BMI groups and with/without prior SGLT2i use [9]
Studies have further demonstrated improvements in metabolic measures such as reduced glycated hemoglobin or HbA1c, fasting plasma glucose levels, self monitored blood glucose profiles, and body weight, which suggests potential value for people looking to achieve better long term health outcomes
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