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We changed salient lysine and arginine residues to alanine in each of the identified patches or combined the patch mutations to generate the 6 A, 7 A, 4 A (within the second AT hook) and 17 A (combination of all three patches) mutants (Fig
Both white and gray matter are lost, best observed in the frontal and temporal lobes of the brain (Hegde et al., 2022
Samuel K
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