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GLP-1 agonists, like GLP-1 itself, stimulate the pancreas to produce more insulin after meals and better regulate blood glucose levels
This 92-person trial is the closest thing to a head-to-head decomposition of the combination that exists, and its most interesting result is the negative one: on the primary glycaemic endpoint, adding cagrilintide to semaglutide did not produce a statistically significant improvement over semaglutide alone
Zmitek K, Zmitek J, Butina MR, Pagacnik T
When this system is not coordinating well, pressure is not managed efficiently and may be pushed outward instead of contained
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