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Western blotting showed that two of the three key enzymes involved in regulating glycolysis, pyruvate kinase L/R-type (PKLR) and phosphofructokinase 1 (PFK-1), were downregulated in male livers compared to controls

It is involved in many biological processes including detoxification of xenobiotics, removal of oxygen-reactive species, regulation of the redox state of cells and the oxidative state of important protein sulfhydryl groups, and regulation of immune function

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