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Observations indicate that MT-1 may modulate the balance of matrix metalloproteinases (MMPs) and their inhibitors, as well as reduce the expression of genes associated with fibrogenesis

Adding more water lowers the concentration in each syringe unit but does not change the total amount in the vial

in Italy assessed the efficacy of a hydrolyzed collagen supplement (5 g per day) to improve skin moisturization, elasticity, and the appearance of wrinkles in 52 women (4060 years of age), where 26 women received the supplement and 26 women were given a placebo for a total of 56 days [41]

This staged approach improves tolerability and adherence, though it means the full therapeutic effect develops more gradually