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The increase in cAMP activates downstream signaling cascades, primarily through protein kinase A (PKA), and upregulates the expression of melanogenic enzymes, resulting in increased eumelanin synthesis and visible skin darkening (Figure 4)
Oral capsule, daily
Because L-carnitine is absorbed via a specific sodium-dependent transporter in the small intestine (known as OCTN2) that can easily become saturated by large single doses, dividing the intake throughout the day maximizes overall intestinal absorption
