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The analog retains full IGF-1 receptor (IGF-1R) agonist activity while displaying extended bioactivity in cell culture and rodent research models
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IgA nephropathy is the most common primary glomerulonephritis worldwide, and a meaningful fraction of patients still progress to kidney failure despite RAAS blockade and SGLT2 inhibitors
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These medications are frequently denied despite strong clinical evidence and FDA-approved indications
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