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Caspase-1 cleaves the N-terminal structural domain of GSDMD, and the cleaved N-terminal fragment inserts into the cell membrane, to form pores, ultimately causing membrane rupture and the release of pro-inflammatory intracellular contents
2009;297:F164755
Understanding the intended use and associated costs is essential for making an informed decision about treatment options
Slley E, Kun S, Szijrt IA, Kertsz M, Wittmann I, Molnr GA
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