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Specifically, the activity and transcript abundance of glutathione peroxidases, which convert GSH to GSSG, increased in infested resistant plants, but the enzymatic activity and transcript abundance of glutathione reductases, which converts GSSG back to GSH, did not change
The synergistic potential of TCM lies in its ability to combat dysbiosis and inflammation, which may enhance the efficacy of conventional drugs, such as by mitigating the gastrointestinal effects of metformin through gut barrier repair, allowing for lower drug doses
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Nevertheless, these potential effects require further research validation, and no definitive clinical application protocols have been established to date
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