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[8] Although not an absolute contraindication, patients with coronary artery disease or unstable angina should only use B-Complex injections containing niacinamide under physician supervision, since high-dose niacin supplements have been linked to arrhythmias in such patients
Metformin-Induced Vitamin B12 Deficiency in Patients With Type-2 Diabetes Mellitus
Why isnt it approved yet
doi: 10.2337/diacare.24.5.875
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