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Alongside insulin and glucagon, special messengers from the gut called gastrointestinal peptides play a powerful role
These are the people who are more hungry in the brain. For others, the hunger signals originate more from the gut and are due to hormonal responses, so these people are more hungry in the gut. People who are hungry in the brain tend to eat very large meals, while those who are hungry in the gut tend to snack more frequently, but usually eat normal portions
These drugs carry FDA approval for adults with a BMI of 30 or greater, or a BMI of 27 or greater with at least one weight-related comorbidity such as type 2 diabetes, hypertension, or dyslipidemia
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