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Meanwhile, in our opinion, programmed cell death, particularly apoptosis, could be added to this axis because the mechanisms of apoptosis and other forms of programmed cell death are inextricably linked to the mitochondria, mTOR, and autophagy

Nuclear factor-kappa B (NF-B) is a transcription factor that binds DNA and induces the transcription of the COX-2 gene, other pro-inflammatory genes, and genes involved in cell proliferation, adhesion, survival, and differentiation

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