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This observation is supported by the expression of GLP-1 receptors in various organs, including the heart and blood vessels 2,43

Research shows certain factors increase the likelihood and duration of semaglutide side effects: Higher doses 2.4 mg Wegovy produce more side effects than 0.5 mg Ozempic Women may report more frequent GI side effects, partly because conditions like IBS are more prevalent in women, and ovarian hormone fluctuations influence gut sensitivity

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