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This finding shaped the expected commercial dosing strategy: start low, go slow
10.18632/aging.101306 242 San Jose-EnerizE.Gimenez-CaminoN.AgirreX.ProsperF
According to the Summary of Product Characteristics (SmPC) approved by the MHRA, nausea is very common (may affect more than 1 in 10 people), whilst vomiting, diarrhoea, abdominal pain, and constipation are common (may affect up to 1 in 10 people)
While weight loss generally benefits heart failure patients, dehydration from gastrointestinal side effects may require adjustment of diuretic therapy
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