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In fact, one of the key changes in physiology associated with longevity is an increased acetylation of mitochondrial proteins [9]
However, when these individuals carry an autoimmune disease like SLE or lupus, a positive ANA blood test, even at a low titer like 1:40 or 1:160, can be essential to detect these diseases
Ferroptosis-related genes (IL-6, IL-1B, EGR1, and ATF3) can be used as biomarkers of synovial tissue hyperplasia in OA [90], and macrophages are active in synovitis inflammation in OA [91]
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