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Tirzepatide has been shown to positively affect blood pressure, possibly due to improved endothelial function or decreased inflammation

The BCPNN analysis further validated these findings, demonstrating that female patients had higher risks of long-term treatment-related adverse reactions, whereas male patients experienced more acute adverse events in the short term

Although baseline and month-6 between-group differences were small, the magnitude of reduction over time was significantly greater in the semaglutide group ( p = 0.001), with a large effect size (d = 0.99) (Table 2)

cDNA was amplified in MicroAmp Optical 96-well reaction plates with SYBR Green PCR Master Mix (Applied Biosystems) on an Applied Biosystems Prism 7000 sequence detection system