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It decreases fat storage and aids in detoxification
All of these substances are prohibited at all times under the USADA Protocol for Olympic and Paralympic Movement Testing, the United States Olympic and Paralympic Committee National Anti-Doping Policies, and the World Triathlon Anti-Doping Rules, all of which have adopted the Code and the World Anti-Doping Agency Prohibited List
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However, through its regulatory function in amino acid metabolism, GPER may exert dual effects on different types of tumor cells: in breast and ovarian cancer cells, GPER activation increases amino acid metabolism, promoting tumor progression [227, 248], whereas in gastric and colorectal cancer cells, GPER activation inhibits key pathways affecting amino acid metabolism, thereby reducing amino acid metabolic utilization and lowering the metabolic state of tumor cells [236]
