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Treatment-effect on eGFR slopes was assessed by fitting a linear regression model per patient, followed by a t-test to compare the slopes between the groups

Studies comparing different GLP-1 agonists found that: GLP1s typically produces 14-15.3kg (around 15%) weight loss at higher doses Liraglutide averages 8% weight reduction after 56 weeks Tirzepatide can achieve 20.9% weight loss during initial treatment periods Real-world results often differ from clinical trials, though

Host Jennifer Smith-Parker, Director of Insights, BioSpace Guests Jane Hughes, President of R&D and Co-founder, Verdiva Bio Jon Rees, CEO and Co-founder, MitoRx Therapeutics Disclaimer: The views expressed in this discussion by guests are their own and do not represent those of their organizations.

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