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It is commonly referred to as a model Ab-mediated disease, on account of the fact that auto-Abs as well as their antigens in most known cases are well characterized [144]
Alpha-lipoic acid seems to help prevent certain kinds of cell damage in the body, and also restores vitamin levels such as vitamin E and vitamin C
Cheff DM, Cheng Q, Guo H, Travers J, Klumpp-Thomas C, Shen M, et al
However, in line with the specificity of CPA, the C-terminal residues of the L585I, L585M, and L585V variants were cleaved in vitro upon exposure to the enzyme for 5 hours at 37 C, as confirmed by liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis of the C-terminal peptides (Supplementary Table 1)
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