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Keeping these issues in mind, at present, we continue to advocate conservative management in low-risk PV (phlebotomy combined with once- or twice-daily aspirin therapy) and include cytoreductive therapy in high-risk patients

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Key Takeaways Heart rate jumps 30+ beats per minute within 10 minutes of standing (normal is under 10 bpm increase), often reaching 120+ bpm from simple position changes

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