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A separate 2025 narrative review by McGuire and colleagues asked a blunter question in its title: "Regeneration or Risk?" [2] Their conclusion: the preclinical evidence is consistently positive, but the absence of human data makes it impossible to generate evidence-based practice guidelines

Meanwhile, an elevated status in reduced glutathione has been found to be linked to a number of processes associated with longevity, with an apparent connection between glutathione and the activity of telomerase, an enzyme which influences cell survival by maintaining telomeres

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