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It should never be influenced by external pressure

In certain cases, other medications, including some antidepressants, may be prescribed off-label

The main practical cautions are its blue-green color (which can tint formulations) and formulation incompatibility with certain other actives notably strong direct-acid vitamin C and high concentrations of exfoliating acids, which can destabilize the copper complex

"Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs"