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Real-world evidence (RWE) is emerging as a powerful tool to: Fill gaps where clinical trials arent feasible Inform off-label use Accelerate treatment development Specialty pharmacists play a central role, capturing patient experiences across the full continuum of care

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Understanding mast cells as neuroimmune amplifiers helps explain why many autoimmune brain disorders present with fluctuating, multisystem symptoms neurological, psychiatric, gastrointestinal, and dermatological and why traditional autoimmunity testing often misses key contributors

Some muscles can receive insufficient perfusion