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Indeed, a pilot study on young patients with ALL suffering from chemo-induced liver toxicity found that treatment with milk thistle led to a "trend towards significant reductions in liver toxicity."24 The researchers state that future studies are needed to zero in on the ideal dosage and duration of treatment, but their findings suggest that milk thistle may be a promising intervention for acute liver injury secondary to chemo

Details of the settings used for UHPLC-QTOF/MS and LC-FTMS were previously described 28

3C), highlighting the advantage of co-targeting parallel nutrient pathways to overcome metabolic plasticity