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The most common skin manifestations include a pale, washed-out complexion from anemia, dryness and cracking (particularly at the corners of the mouth), hyperpigmented patches on the hands or face, and glossitis a swollen, smooth, unusually red tongue
While animal and in vitro studies have examined its activity, large-scale human clinical trials are limited, and its full safety and efficacy profile has not been established
doi:10.1007/978-0-387-78518-9_18
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