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When GLP-1 medications are contraindicated GLP-1 receptor agonists are contraindicated if you have: A personal or family history of medullary thyroid cancer A genetic condition called Multiple Endocrine Neoplasia type 2 (MEN-2) This warning comes from animal studies where rodents developed C-cell tumors

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Table 3 Summary of the main studies with combined use of GLP1-AR and SGLT2 inhibitors

It is commonly associated with muscle health and recovery, making it an ideal choice among those with active lifestyles