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The Gila monster ( Heloderma suspectum ) spends 95% of its life underground, surviving on massive seasonal feasts during which it consumes up to a third of its body weight in a single sitting

Eventually this excess debris can lead to cell death

Once the weight settles, the loss usually eases off and the hair comes back on its own

So, Secher asked, does that mean that these are the only regions that are activated by GLP-1 receptor agonists? She and her team do not believe that this is the case, she said, because when you have interaction with one neuron, this can communicate to many other neurons in deeper layers of the brain. To test whether that was happening, her team used c-Fos, a protein that can be used as a marker for neuronal activation