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Arginine has been reported to alleviate pulmonary inflammation by improving mitochondrial function, enhancing ATP generation, and reducing DNA damage [62, 63]
To corroborate these findings on a functional level, we isolated activated ILC2s from IL-33 challenged BALB/c mice ( Figure 3A ), which were then incubated for 24h with either an MT1 agonist (Ramelteon), MT1 antagonist (S-26131), MT2 agonist (Tasimelteon), MT2 antagonist (4-P-PDOT) and/or melatonin ( Figures 3BE )
Since there was no commercially available rat UGT2B1 antibody, we used UGT2B7 antibody to detect the protein expression of rat UGT2B1 (homology with human UGT2B7)
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