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Conditioned taste aversion study Lean mice were trained to consume their daily water requirements over 1 h, then given access to saccharin-sweetened Kool-Aid, followed immediately by IP injection of a potentially aversive stimulus (vehicle, agonist, or LiCl 0.15 M in a volume equivalent to 2% body weight as positive control)

This dual mechanism may enhance outcomes for GERD specifically compared to purely systemic delivery

These pathways may include immunomodulatory activity, tissue remodeling, and cellular proliferation in research subjects in experimental trials

Retatrutide is an investigational, once-weekly injectable drug that is being reviewed for the management of obesity and type 2 diabetes