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The most important ones have been enumerated in [Box 1]
Injection site rotation: Move sites week to week (abdomen, thighs, upper arms), keeping each shot at least 1 inch from the last to limit irritation and prevent lipohypertrophy [15]
These stressors could be not getting sufficient sleep, smoking, food intolerances, diets high in sugars and processed foods, excess alcohol intake and hormone or immune imbalances
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