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O uso fora das indicaes aprovadas (off-label) tambm tem gerado debates ticos, legais e de acesso
He was subsequently switched to oral semaglutide 14 mg and did not experience recurrence, suggesting the effect may be dose-dependent rather than strictly class-dependent
In antisense oligonucleotide (ASO) therapies, a C9orf72 sense transcript-targeting antisense oligonucleotide BIIB078 exhibited robust efficacy in the preclinical mouse and cellular models (Donnelly et al., 2013
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