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Omeprazole is formulated as an enteric-coated preparation, designed to resist degradation by stomach acid and release its active ingredient in the more alkaline environment of the small intestine

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Although uncontrolled hypothyroidism is associated with increased stroke risk via mechanisms, such as increased vascular resistance, endothelial dysfunction, dyslipidemia, and a pro-thrombotic state [68], the increased stroke risk may be attenuated by the potential cerebrovascular protective effects of GLP-1RA [69]