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Changes in skeletal muscle mass have been seen in patients who lose weight with GLP-1RA medications with up to 4.513.2% lean muscle loss or 2050% of the total weight loss [35, 52, 71, 72]
For patients undergoing larger reconstructive procedures or combined surgeries under monitored anesthesia or general anesthesia, I defer to anesthesia colleagues about whether a temporary hold is necessary
For antidepressants like SSRIs, absorption may be delayed, but dose adjustments are rarely needed
Thornalley, P
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