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According to Kannt & Pfenninger in Frontiers in Physiology , NAD is a critical coenzyme in mitochondrial energy metabolism, and strategies that preserve NAD have wide-ranging effects on health and performance (Kannt & Pfenninger, Frontiers in Physiology )
10.1016/S0006-3495(99)77369-8 82
Vitamin B12 is important for proper digestion, and a deficiency can lead to digestive issues such as diarrhea, constipation, and loss of appetite
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