The NHS and NICE do not recommend peptides for ED, instead advocating proven treatments like PDE5 inhibitors (sildenafil, tadalafil)
Starting at a lower dose is commonly used to assess individual tolerance, since higher starting amounts may be associated with temporary effects such as insomnia , restlessness/anxiety , or fatigue during the adjustment phase
Compounded versions from telehealth platforms like Elevate Health are substantially less expensive because they are not brand-name FDA-approved products and are not marketed by pharmaceutical manufacturers with associated research, development, and marketing costs
Ashby D, Borman N, Burton J, Corbett R, Davenport A, Farrington K et al (2019) Renal Association Clinical Practice Guideline on Haemodialysis