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More serious B12 deficiencies have the potential to impair heart and neurological function, leading to a wide range of serious symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia and changes in reflexes
To help reduce the risk of lactic acidosis while taking Metformin, make sure to take the medication with meals to minimize stomach discomfort
A review in Trends in Endocrinology & Metabolism asked: "Can kisspeptin be a new treatment for sexual dysfunction?" The authors highlighted therapeutic potential but noted the short half-life (~28 minutes) as the primary delivery challenge (ScienceDirect, 2025)
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