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For a 50-year-old female with obesity, type 2 diabetes, and hypertension who is currently taking tirzepatide (Mounjaro) 12.5 mg weekly, phentermine 37.5 mg daily, losartan 50 mg, and spironolactone 50 mg, is it appropriate and safe to increase tirzepatide to 15 mg, continue phentermine for another month, and maintain her current antihypertensive regimen?

Subjects were considered generally healthy based on medical history, physical examination, electrocardiogram and clinical laboratory tests

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Certain peptides can regulate immune activity, decrease inflammatory cytokines, and promote tissue regeneration in reproductive tissues