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Kim MH, Kim EH, Jung HS, Yang D, Park EY, Jun HS
Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin'
The peptide incorporates specific amino acid substitutions that make it resistant to dipeptidyl peptidase-4 (DPP-4), the enzyme primarily responsible for degrading natural GHRH
Disrupted ovulation The hormonal imbalances in PCOS can disrupt the normal ovulation process, leading to the formation of small cysts on the ovaries
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