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Clinical trials are testing them for heart disease, sleep apnea, liver disease, even addiction
To create viable therapeutics, researchers had to engineer GLP-1 analogs that resist enzymatic breakdown and persist long enough to exert physiological effects
Next-Generation Therapies Research at UAB and other institutions is exploring even more advanced formulations from oral versions of semaglutide to triple-receptor medications like retatrutide that could further enhance weight management and metabolic outcomes
doi: 10.3109/00365521.2015.1050691
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