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Good news: With planning and monitoring, most people do just fine on the combination

Abbreviations T2DM: Type 2 diabetes mellitus GLP-1RAs: Glucagon-like peptide-1 receptor agonists GIP: Glucose-dependent insulinotropic peptide hsCRP: High-sensitivity C-reactive protein IL: Interleukin MD: Mean difference CI: Confidence intervals SE: Standard error MASLD: Metabolic dysfunction-associated steatotic liver disease MCP-1: Monocyte chemoattractant protein-1 References NCD Risk Factor Collaboration (NCD-RisC)

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The medication acts on receptors in the brain to reduce hunger signals and increase satiety, while simultaneously slowing the rate at which food leaves the stomach