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If supplements are the cause, reducing or stopping supplementation is the only step needed

Weeks 13+: 10-12 mg per week (maintenance) The highest clinical doses

These include reducing oxidative stress and inflammation, improving plasma lipid profile, and control of blood pressure and blood glucose levels ( FIGURE 8 Evidence Studies in cells and animals have supported a direct role of folic acid to enhance NO availability via effects on eNOS and DHFR expression and activity (Stroes et al., 2000

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