Plus, flaring up IBD symptoms or simply having poor digestion can cause stomach pain, [7] lower sleep quality, [8] and potentially a whole slew of other problems, [9] which won't help you recover after workouts or achieve your best performance in the gym
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Additionally, GLP-1 activates related intracellular signaling pathways, promoting -cell regeneration, inhibiting -cell apoptosis, and improving -cell function, thereby lowering blood glucose levels, with its effects being glucose concentration-dependent (58, 59)
The authors found no significant increase in the LLA for SGLT2 inhibitors compared to GLP-1 RAs, while they were associated with a lower risk compared to dipeptidyl peptidase-4 (DPP-4) inhibitors, but a higher risk compared to sulphonylureas [99]