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10.1038/s41598-023-34642-6 19
GLP-1 receptor agonists such as semaglutide and the dual GIP/GLP-1 agonist tirzepatide act on appetite, satiety, and gastric emptying, with evidence from programs like STEP (NEJM, 2021), SURMOUNT (NEJM, 2022), and SURMOUNT-OSA (NEJM, 2024)
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Precision is also paramount in terms of getting optimal treatment for people, and the appeal of different treatments might differ amongst people. GLP-1 Treatments Face Hurdles While GLP-1s offer promising benefits for some patients, significant barriers remain regarding supply, cost, and insurance coveragechallenges that Saunders describes as humongous limitations. Novo Nordisks Ozempic and Wegovy have been on the FDAs drug shortage list since 2022
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