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The causes can be broadly categorised into exogenous (external) and endogenous (internal) factors, with the latter being of greater clinical significance
The injection itself is quick and usually takes just a few minutes
Storage figures above come from vendor guidance rather than a published stability assay: unmixed powder at or below 25 C away from light, mixed solution refrigerated at 2 8 C and used within about 28 days
The Phase 2 trial used subcutaneous injection into the abdomen, thigh, or upper arm on a rotating basis to minimize local reactions
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